Article

Emerging Biomarkers and Potential Therapeutics of the BCL-2 Protein Family: The Apoptotic and Anti-Apoptotic Context

2023-02-22

Abstract excerpt

Apoptosis, also known as the programmed death of cells, is responsible for maintaining the homeostasis of tissues and this function is carried out by caspases. The process of apoptosis is carried out via two distinct pathways: the extrinsic pathway, which is governed by death receptors, and the intrinsic pathway, also known as the mitochondrial pathway. The BCL-2 protein family encoded by the BCL-2 gene, located a...

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Literature Corpus work: e3568b06-44c3-57f8-aa4d-bca1fddffee4
DOI: 10.20944/preprints202302.0387.v1

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