Back to search

Article

Real-time predictions of reservoir size and rebound time during antiretroviral therapy interruption trials for HIV

2016-01-28

Abstract excerpt

Monitoring the efficacy of novel reservoir-reducing treatments for HIV is challenging. The limited ability to sample and quantify latent infection means that supervised antiretroviral therapy (ART) interruption studies are generally required. Here we introduce a set of mathematical and statistical modeling tools to aid in the design and interpretation of ART-interruption trials. We show how the likely size of the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a3700e32-35f5-535e-8094-c985000c28d0
DOI
10.1101/038091
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Real-time predictions of reservoir size and rebound time during antiretroviral therapy interruption trials for HIVDOI 10.1101/038091
Select a neighboring publication to make it the new centre.