Article

Identification of molecular determinants of gene-specific bursting patterns by high-throughput imaging screens

2024-06-08

Abstract excerpt

<h4>Summary</h4> Stochastic transcriptional bursting is a universal property of active genes. While different genes exhibit distinct bursting patterns, the molecular mechanisms for gene-specific stochastic bursting are largely unknown. We have developed and applied a high-throughput-imaging based screening strategy to identify cellular factors and molecular mechanisms that determine the bursting behavior of human...

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Literature Corpus work: a3499e7a-efcb-5886-b66d-c3feb584781a
DOI: 10.1101/2024.06.08.597999

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