Article

Increased aperiodic gamma power in young boys with Fragile X is associated with better language ability

2020-10-13

Abstract excerpt

<h4>ABSTRACT</h4> The lack of identified clinical biomarkers in Fragile X Syndrome (FXS), the most common inherited form of intellectual disability, has limited the successful translation of bench-to-bedside therapeutics. While numerous drugs have shown promise in reversing synaptic and behavioral phenotypes in mouse models of FXS, none have demonstrated clinical efficacy in humans. Electroencephalographic (EEG) m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9bd3c4bc-000e-5961-bbb6-7be212abb052
DOI: 10.1101/2020.10.08.20209536

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Increased aperiodic gamma power in young boys with Fragile X is associated with better language abilityDOI 10.1101/2020.10.08.20209536Read

Increased aperiodic gamma power in young boys with Fragile X Syndrome is associated with better language abilitySemantic proximity Read

Electroencephalography signals in a female Fragile X Syndrome mouse modelSemantic proximity Read

A human electrophysiological biomarker of Fragile X Syndrome is shared in V1 of <i>Fmr1</i> KO mice and caused by loss of FMRP in cortical excitatory neuronsSemantic proximity Read

Alterations in Electroencephalography Signals in Female Fragile X Syndrome Mouse Model on a C57Bl/6J BackgroundSemantic proximity Read

Gaboxadol Increases Resting Theta and Alpha Power without Affecting Evoked Responses in Fragile X Syndrome in a Home-based SettingSemantic proximity Read

Alpha oscillations are dysrhythmic in Fragile X syndromeSemantic proximity Read

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome.Semantic proximity Read

Behavioral Phenotype Associations With Resting State EEG Signal Complexity and Power Spectral Density in Fragile X Syndrome.Semantic proximity Read

Validating brain activity measures as reliable indicators of individual diagnostic group and genetically mediated sub-group membership Fragile X SyndromeSemantic proximity Read

Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome.Semantic proximity Read

Empirical Frequency Bound Derivation Reveals Prominent Mid-Frontal Alpha Associated with Neurosensory Dysfunction in Fragile X SyndromeSemantic proximity Read

Empirical Frequency Bound Derivation Reveals Prominent Mid-Frontal Alpha Associated with Neurosensory Dysfunction in Fragile X SyndromeSemantic proximity Read