Article

Alterations in Electroencephalography Signals in Female Fragile X Syndrome Mouse Model on a C57Bl/6J Background

2025-07-10

Abstract excerpt

<h4>Background</h4> Fragile X Syndrome (FXS), the most common monogenic cause of autism spectrum disorder, arises from FMR1 gene silencing and exhibits pronounced sex differences in prevalence and phenotypic severity. Electroencephalography (EEG) has emerged as a promising translational biomarker for FXS pathophysiology, yet prior research has predominantly focused on male cohorts. In the widely used C57Bl/6J (B6...

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Literature Corpus work: 9acfb8f3-1eda-5329-ac0b-202d51684973
DOI: 10.1101/2025.07.07.662836

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