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Mouse mutants in schizophrenia risk genes <i>GRIN2A</i> and <i>AKAP11</i> show EEG abnormalities in common with schizophrenia patients

2022-04-07

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<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Schizophrenia is a heterogeneous psychiatric disorder with a strong genetic basis, whose etiology and pathophysiology remain poorly understood. Exome sequencing studies have uncovered rare, loss-of-function variants that greatly increase risk of schizophrenia [1], including loss-of-function mutations in GRIN2A (aka GluN2A or NR2A , encoding the NMDA receptor subunit 2A) a...

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Literature Corpus work
583cf777-ce67-5554-b2c4-208b83675bd1
DOI
10.1101/2022.04.05.487037
Open publication

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Mouse mutants in schizophrenia risk genes <i>GRIN2A</i> and <i>AKAP11</i> show EEG abnormalities in common with schizophrenia patientsDOI 10.1101/2022.04.05.487037
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