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Optimizing Fingolimod Dosing in STZ-Induced Cognitive Impairment: Divergent Behavioral and Histopathological Responses Reveal a Narrow Neuroprotective Window

2025-12-18

Abstract excerpt

<title>Abstract</title> <p> <bold>Background/Objective:</bold> Fingolimod, an S1P receptor modulator, is neuroprotective and anti-inflammatory in animal models of neurodegenerative disorders; its optimal dosage regimen for cognitive dysfunction is yet to be defined. The impact of fingolimod on cognitive function, neuroinflammation, oxidative levels, as well as hippocampal morphology, was evaluated in the strept...

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Literature Corpus work
a2cdf58f-937b-5393-a860-2f4678d38576
DOI
10.21203/rs.3.rs-8382715/v1
Open publication

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Optimizing Fingolimod Dosing in STZ-Induced Cognitive Impairment: Divergent Behavioral and Histopathological Responses Reveal a Narrow Neuroprotective WindowDOI 10.21203/rs.3.rs-8382715/v1
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