Article
Effects of fingolimod administration in a genetic model of cognitive deficits.
Journal of neuroscience research - 1 May 2017
Becker-Krail D, Farrand A Q, Boger H A, Lavin A
Abstract excerpt
Notwithstanding recent advances, cognitive impairments are among the most difficult-to-treat symptoms in neuropsychiatric disorders. Deficits in information processing contributing to memory and sociability impairments are found across neuropsychiatric-related disorders. Previously, we have shown that mutations in the DTNBP1 gene (encoding dystrobrevin-binding protein 1 [dysbindin-1]) lead to abnormalities in...
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