Article

Single-cell DNA methylome and 3D genome atlas of the human subcutaneous adipose tissue

2024-11-03

Abstract excerpt

Human subcutaneous adipose tissue (SAT) contains a diverse array of cell-types; however, the epigenomic landscape among the SAT cell-types has remained elusive. Our integrative analysis of single-cell resolution DNA methylation and chromatin conformation profiles (snm3C-seq), coupled with matching RNA expression (snRNA-seq), systematically cataloged the epigenomic, 3D topology, and transcriptomic dynamics across t...

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Literature Corpus work: a2c2f641-adfa-570b-819a-d575a01bc2f3
DOI: 10.1101/2024.11.02.621694

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