Article

Production of interspecies somatic/pluripotent heterokaryons using polyethylene glycol (PEG) and selection by imaging flow cytometry for the study of nuclear reprogramming

2019-05-31

Abstract excerpt

<h4>ABSTRACT</h4> Fusion of somatic cells to pluripotent cells such as mouse embryonic stem (ES) cells induces reprogramming of the somatic nucleus, and can be used to study the effect of trans -acting factors from the pluripotent cell on the somatic nucleus. Moreover, fusion of cells from different species permits the identification of the transcriptome of each cell, so the gene expression changes can be monito...

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Literature Corpus work: a2afdaf8-81e8-58fc-91c3-037762e52114
DOI: 10.1101/655621

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