Article

Ephrin Forward Signaling Controls Interspecies Cell Competition in Pluripotent Stem Cells

2024-06-03

Abstract excerpt

<h4>Summary</h4> In the animal kingdom, evolutionarily conserved mechanisms known as cell competition eliminate unfit cells during development. Interestingly, cell competition also leads to apoptosis of donor cells upon direct contact with host cells from a different species during interspecies chimera formation. The mechanisms underlying how host animal cells recognize and transmit cell death signals to adjacent...

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Literature Corpus work: 481e7b34-6c40-5b30-b3e0-a922148a1bc7
DOI: 10.1101/2024.06.02.597057

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