Article

The press-assisted fusion scheme greatly reduces the amount of HVJ-E required in mitochondrial replacement techniques

2022-11-23

Abstract excerpt

<h4>Background: </h4> Mitochondrial replacement techniques (MRTs) afford pathogenic mitochondria carried women an opportunity to have related disease-free offspring with a genetic link. Among the fusion methods, HVJ-E-induced fusion has been considered the most promising method for MRTs clinical translation. Although HVJ-E has been confirmed to have no RNA activity, a decrease in blastocyst quality was observed in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3e3de4ea-1dfe-5f86-bfa7-65ed5218ff43
DOI: 10.21203/rs.3.rs-2292711/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The press-assisted fusion scheme greatly reduces the amount of HVJ-E required in mitochondrial replacement techniquesDOI 10.21203/rs.3.rs-2292711/v1Read

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variantsSemantic proximity Read

Mitochondrial replacement therapy and assisted reproductive technology: A paradigm shift toward treatment of genetic diseases in gametes or in early embryosSemantic proximity Read

Three-parent babies: Mitochondrial replacement therapies.Semantic proximity Read

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized mitochondrial deliverySemantic proximity Read

Lessons Learned from Somatic Cell Nuclear TransferSemantic proximity Read

Ooplasmic transfer in human oocytes: efficacy and concerns in assisted reproductionSemantic proximity Read

Melatonin Protects Rabbit Somatic Cell Nuclear Transfer (SCNT) Embryos from Electrofusion DamageSemantic proximity Read

Harnessing endogenous repair mechanisms for targeted gene knock-in of bovine embryosSemantic proximity Read

Mitochondrial replacement: from basic research to assisted reproductive technology portfolio tool-technicalities and possible risks.Semantic proximity Read

Transfer of mitochondrial DNA into the nuclear genome during gene editingSemantic proximity Read

Reprogramming mediated by stem cell fusionSemantic proximity Read

A stress-reduced passaging technique improves the viability of human pluripotent cellsSemantic proximity Read