Article

A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and their Differentiated Derivatives

2020-01-08

Abstract excerpt

<h4>Summary</h4> Recent single cell analyses have found molecular heterogeneities within populations of pluripotent stem cells (PSCs). A tool that tracks single cell lineages and their phenotypes longitudinally would reveal whether heterogeneity extends beyond molecular identity. Hence, we generated a stable Cre-inducible rainbow reporter human PSC line that provides up to 18 unique membrane-targeted fluorescent...

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Literature Corpus work: 0a6efedf-2161-5f51-bb89-1fee7c5d8291
DOI: 10.1101/2020.01.08.896290

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