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Reprogramming mediated by stem cell fusion

1 Apr 2005

Abstract excerpt

Advances in mammalian cloning prove that somatic nuclei can be reprogrammed to a state of totipotency by transfer into oocytes. An alternative approach to reprogram the somatic genome involves the creation of hybrids between somatic cells and other cells that contain reprogramming activities. Potential fusion partners with reprogramming activities include embryonic stem cells, embryonic germ cells, embryonal...

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PMID: 15963252
DOI: 10.1111/j.1582-4934.2005.tb00358.x

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