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Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits

2025-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Genetic research on nicotine dependence has utilized multiple assessments that are in weak agreement. We conducted a genome-wide association study of nicotine dependence defined using the Diagnostic and Statistical Manual of Mental Disorders (DSM-NicDep) in 61,861 individuals (47,884 of European ancestry, 10,231 of African ancestry, 3,746 of East Asian ancestry) and compared the results to other...

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Literature Corpus work
a222c339-aab5-58a3-afe0-2a352ce468d8
DOI
10.1101/2025.01.29.25320962
Open publication

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Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traitsDOI 10.1101/2025.01.29.25320962
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