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Article

Genome-wide single nucleotide polymorphism heritability of nicotine dependence as a multidimensional phenotype.

Psychological medicine - 1 Jul 2016

Bidwell L C, Palmer R H C, Brick L, McGeary J E, Knopik V S

Abstract excerpt

BACKGROUND: Heritability estimates from twin studies of the multi-faceted phenotype of nicotine dependence (ND) range from moderate to high (31-60%), but vary substantially based on the specific ND-related construct examined. The current study estimated the aggregate role of common genetic variants on key ND constructs. METHOD: Genomic-relationship-matrix restricted maximum likelihood (GREML) was used to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 27052577
DOI: 10.1017/S0033291716000453
PMCID: PMC4925274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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