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Article

Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes.

Drug and alcohol dependence - 1 Jun 2012

Chen Li-Shiun, Xian Hong, Grucza Richard A, Saccone Nancy L, Wang Jen C, Johnson Eric O, Breslau Naomi, Hatsukami Dorothy, Bierut Laura J

Abstract excerpt

BACKGROUND: The associations between nicotine dependence and specific variants in the nicotinic receptor CHRNA5-A3-B4 subunit genes are irrefutable with replications in many studies. The relationship between the newly identified genetic risk variants for nicotine dependence and comorbid psychiatric disorders is unclear. We examined whether these genetic variants were associated with comorbid disorders and whether...

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Source

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Identifiers

PMID: 22336398
DOI: 10.1016/j.drugalcdep.2012.01.014
PMCID: PMC3376673

Genes

CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes.PMID 22336398Read ↗

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