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Article

Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.

Biological psychiatry - 1 Mar 2015

Gelernter Joel, Kranzler Henry R, Sherva Richard, Almasy Laura, Herman Aryeh I, Koesterer Ryan, Zhao Hongyu, Farrer Lindsay A

Abstract excerpt

BACKGROUND: We report a genome-wide association study (GWAS) of nicotine dependence defined on the basis of scores on the Fagerström Test for Nicotine Dependence in European-American (EA) and African-American (AA) populations. METHODS: Our sample, from the one used in our previous GWAS, included only subjects who had smoked >100 cigarettes lifetime (2114 EA and 2602 AA subjects) and an additional 927 AA and 2003...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25555482
DOI: 10.1016/j.biopsych.2014.08.025
PMCID: PMC4386684

Genes

DISC1
CHRNA3
CHRNA5
CHRNB4
CSGALNACT1
DLC1
INTS10
TSNAX

Provenance

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