Article

Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression

2025-08-07

Abstract excerpt

<h4>ABSTRACT</h4> Prostate carcinoma (PCa) is the most common cancer of men, associated with a still unresolved issue of accurate risk-stratification. While recent advances in omics technologies have provided clues as to how molecular changes shape the onset and progression of PCa, it remains largely unclear whether germline variants and somatic mutations cooperate to contribute to PCa progression and outcome. Th...

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Literature Corpus work: a1d62b0d-4a4d-55e9-9624-43d310ee0870
DOI: 10.1101/2025.08.05.668679

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