Article
DNA alterations in the tumor genome and their associations with clinical outcome in prostate cancer.
Asian journal of andrology - 1 Jan 2000
Liu Wennuan
Abstract excerpt
Although most prostate cancer (PCa) cases are not life-threatening, approximately 293 000 men worldwide die annually due to PCa. These lethal cases are thought to be caused by coordinated genomic alterations that accumulate over time. Recent genome-wide analyses of DNA from subjects with PCa have revealed most, if not all, genetic changes in both germline and PCa tumor genomes. In this article, I first review the...
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