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Prostate cancer genomics by high-throughput technologies: genome-wide association study and sequencing analysis.

Endocrine-related cancer - 1 Aug 2013

Nakagawa Hidewaki

Abstract excerpt

Prostate cancer (PC) is the most common malignancy in males. It is evident that genetic factors at both germline and somatic levels play critical roles in prostate carcinogenesis. Recently, genome-wide association studies (GWAS) by high-throughput genotyping technology have identified more than 70 germline variants of various genes or chromosome loci that are significantly associated with PC susceptibility. They...

Topics

Animals
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Genotype
High-Throughput Screening Assays
Humans
Male
Prostatic Neoplasms
Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23625613
DOI: 10.1530/ERC-13-0113

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