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Article

Uncovering somatic genetic drivers in prostate cancer through comprehensive genome-wide analysis.

GeroScience - 1 Jun 2025

Lin Lede, Li Zhen, Chen Kai, Shao Yanxiang, Li Xiang

Abstract excerpt

Given that hereditary prostate cancer (PCa) accounts for only a small fraction of PCa phenotypes, there is still a substantial journey ahead in exploring the somatic genetic drivers contributing to sporadic PCa. The expression quantitative trait loci (eQTLs) data were sourced from the GTEx dataset for prostate-specific genes, and the summary statistic information was collected for 5854 genes. Genetic associations...

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Source

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Identifiers

PMID: 40156736
DOI: 10.1007/s11357-025-01623-8
PMCID: PMC12181140

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