Back to search

Article

Integrated multi-omics analyses identify key anti-viral host factors and pathways controlling SARS-CoV-2 infection

2022-08-15

Abstract excerpt

<title>Abstract</title> <p>Host anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely unknown due to the biases of previous large-scale studies toward pro-viral host factors. To fill in this knowledge gap, we performed a genome-wide CRISPR dropout screen and integrated analyses of the multi-omics data of the CRISPR screen, genome-wide association studies, single-cell RNA-seq, an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
30323250-8c48-5953-8918-9e60c510aa88
DOI
10.21203/rs.3.rs-1910932/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrated multi-omics analyses identify key anti-viral host factors and pathways controlling SARS-CoV-2 infectionDOI 10.21203/rs.3.rs-1910932/v1
Select a neighboring publication to make it the new centre.