Article

Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis

2021-01-08

Abstract excerpt

Homozygous nonsense mutations in CEP55 are associated with several congenital malformations that lead to perinatal lethality suggesting that it plays a critical role in regulation of embryonic development. CEP55 has previously been studied as a critical regulator of cytokinesis predominantly in transformed cells and its deregulation is linked to carcinogenesis. However, its molecular functions during embryonic dev...

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Literature Corpus work: a152fc41-2562-5d5a-ba4e-93165e1aef2e
DOI: 10.1101/2021.01.08.425857

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