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Gene-Specific Analysis of Clonal Hematopoiesis Identifies ASXL1 as a Risk Factor for Lung Cancer

2026-05-26

Abstract excerpt

<h4>Introduction</h4> Clonal hematopoiesis of indeterminate potential (CHIP) is a recognized risk factor for hematologic malignancies, but its contribution to different types of solid cancers remains incompletely defined. <h4>Methods</h4> Here, we performed a systematic, gene-specific analysis of CHIP across 19 common solid cancer types using two large population-based cohorts, the UK Biobank and All of Us with...

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Literature Corpus work
a14d5282-7a47-525e-8ad7-d4b60e914392
DOI
10.64898/2026.05.21.726910
Open publication

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Gene-Specific Analysis of Clonal Hematopoiesis Identifies ASXL1 as a Risk Factor for Lung CancerDOI 10.64898/2026.05.21.726910
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