Clonal Hematopoiesis and Risk of Incident Lung Cancer.

doi:10.1200/JCO.22.00857

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Article

Clonal Hematopoiesis and Risk of Incident Lung Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Mar 2023

Tian Ruiyi, Wiley Brian, Liu Jie, Zong Xiaoyu, Truong Buu, Zhao Stephanie, Uddin Md Mesbah, Niroula Abhishek, Miller Christopher A, Mukherjee Semanti, Heiden Brendan T, Luo Jingqin, Puri Varun, Kozower Benjamin D, Walter Matthew J, Ding Li, Link Daniel C, Amos Christopher I, Ebert Benjamin L, Govindan Ramaswamy, Natarajan Pradeep, Bolton Kelly L, Cao Yin

Abstract excerpt

PURPOSE: To prospectively examine the association between clonal hematopoiesis (CH) and subsequent risk of lung cancer. METHODS: Among 200,629 UK Biobank (UKBB) participants with whole-exome sequencing, CH was identified in a nested case-control study of 832 incident lung cancer cases and 3,951 controls (2006-2019) matched on age and year at blood draw, sex, race, and smoking status. A similar nested case-control...

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PMID: 36480766
DOI: 10.1200/JCO.22.00857
PMCID: PMC9995101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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