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Article

Chronic β-catenin O-GlcNAcylation is a driver of hypertrophy in diabetic cardiomyopathy

2026-07-23

Abstract excerpt

<title>Abstract</title> <p>Background The incidence of heart failure is approximately 2.5-fold higher in patients with type 2 diabetes than in non-diabetic individuals. Diabetic cardiomyopathy is characterized by diastolic dysfunction and left ventricular hypertrophy. The diabetic heart exhibits insulin resistance, leading to impaired glucose uptake and oxidation and, consequently, to intracellular glucose overl...

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Literature Corpus work
a1251f3c-2069-56c6-af93-9eca3bdf6a26
DOI
10.21203/rs.3.rs-10392150/v1
Open publication

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Chronic β-catenin O-GlcNAcylation is a driver of hypertrophy in diabetic cardiomyopathyDOI 10.21203/rs.3.rs-10392150/v1
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