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A Transient Increase in Cardiomyocyte Protein O-GlcNAcylation Enhances Susceptibility to Pressure Overload-Induced Cardiac Remodeling

2025-06-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> The observation that diabetic patients always under tight-glycemic control consistently show better cardiovascular disease outcomes compared to patients who transition to tight-glycemic control after prior conventional glycemic control lead to the concept of metabolic memory. Mechanisms such as epigenetics possibly mediate the lasting metabolic memory effects, our understand...

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Literature Corpus work
3f28cbe5-64ae-57ee-923a-5666e5b42319
DOI
10.1101/2025.06.04.657956
Open publication

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A Transient Increase in Cardiomyocyte Protein O-GlcNAcylation Enhances Susceptibility to Pressure Overload-Induced Cardiac RemodelingDOI 10.1101/2025.06.04.657956
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