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Article

Interferons as Inducers of Apoptosis in Malignant Cells

1 Apr 2013

Abstract excerpt

Discovered as antiviral cytokines, interferons (IFNs) are now also recognized for their capacity to inhibit the growth of malignant cells via activation of programmed cell death, better known as apoptosis. In this review, we will cover recent advances made in this field, as it pertains to the various proposed mechanisms of IFN-induced apoptosis and the characterization of IFN-responsive genes not previously known...

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PMID: 23570382
DOI: 10.1089/jir.2012.0110

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