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Article

Interferon α in cancer immunoediting: From elimination to escape

7 Jan 2020

Abstract excerpt

Interferon α (IFNα) is a cytokine that mediates diverse immune responses to tumours. It is the oldest immune-based oncologic drug and has been widely used to treat various malignancies in humans. Yet, the use of IFNα in cancer therapy has only resulted in limited success and even led to worse clinical outcomes under certain instances. The emergence of the cancer immunoediting concept-which implicates the host...

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PMID: 31909839
DOI: 10.1111/sji.12863

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