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Article

Interferon Lambda: A New Sword in Cancer Immunotherapy

1 Jan 2011

Abstract excerpt

The discovery of the interferon-lambda (IFN-λ) family has considerably contributed to our understanding of the role of interferon not only in viral infections but also in cancer. IFN-λ proteins belong to the new type III IFN group. Type III IFN is structurally similar to type II IFN (IFN-γ) but functionally identical to type I IFN (IFN-α/β). However, in contrast to type I or type II IFNs, the response to type III...

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PMID: 22190970
DOI: 10.1155/2011/349575

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