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Interferon Alfa Receptor Expression and Growth Inhibition by Interferon Alfa in Human Liver Cancer Cell Lines

1 Jun 1999

Abstract excerpt

Type I interferon (IFN) receptor consists of two chains (Hu-IFN-alphaR1 and Hu-IFN-alphaR2), and Hu-IFN-alphaR2 takes a soluble (Hu-IFN-alphaR2a), short (Hu-IFN-alphaR2b), or long (Hu-IFN-alphaR2c) form. We examined the expression of type I IFN receptor, the growth-suppression effect of IFN-alpha, and their relationship in 13 liver cancer cell lines. With reverse-transcription polymerase chain reaction (RT-PCR)...

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PMID: 10347112
DOI: 10.1002/hep.510290624

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