Article

Clinical mechanism of ribavirin action in Hepatitis C treatment: insights from the STOPHCV-1 randomised trial

2026-04-15

Abstract excerpt

<h4>Background</h4> Ribavirin is a guanosine analogue with clinical antiviral activity against a range of RNA viruses including hepatitis C virus (HCV), respiratory syncytial virus and Lassa virus. Several potential mechanisms of action have been proposed, but there is limited data supporting them clinically. <h4>Methods</h4> We studied 196 HCV-infected participants from a trial of short-course directly antivira...

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Literature Corpus work: a0d8cee5-2f41-561f-87b8-40c175749fae
DOI: 10.64898/2026.04.14.26350846

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