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Article

In-depth longitudinal study on hepatitis E virus evolution in chronic infection with ribavirin treatment failure

2026-04-06

Abstract excerpt

<title>Abstract</title> <p>Hepatitis E virus (HEV) can persist in immunocompromised patients, and ribavirin therapy may fail when resistance-associated variants emerge in the viral population. The evolutionary dynamics towards treatment failure remain poorly defined because comparative clinical and in vitro systems are scarce. Our study employed longitudinal deep sequencing of a chronic hepatitis E transplant rec...

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Literature Corpus work
77f6605f-007f-5993-b656-3ef7aa91422e
DOI
10.21203/rs.3.rs-9246305/v1
Open publication

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In-depth longitudinal study on hepatitis E virus evolution in chronic infection with ribavirin treatment failureDOI 10.21203/rs.3.rs-9246305/v1
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