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Dynamics of drug delivery determines course of evolution of antibiotic responses in bacteria

2023-11-30

Abstract excerpt

To adjust to sudden shifts in conditions, microbes possess regulated genetic mechanisms that sense environmental challenges and induce the appropriate responses. The initial evolution of microbes in new environments is thought to be driven by regulatory mutations, but it is not clear how this evolution is affected by how quickly conditions change (i.e. dynamics). Here, we perform experimental evolution on continuo...

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Literature Corpus work
a0d29fd3-d3d6-5192-87ef-110a3035a064
DOI
10.1101/2023.11.29.569327
Open publication

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Dynamics of drug delivery determines course of evolution of antibiotic responses in bacteriaDOI 10.1101/2023.11.29.569327
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