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Article

Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection.

PLoS biology - 1 Oct 2019

Card Kyle J, LaBar Thomas, Gomez Jasper B, Lenski Richard E

Abstract excerpt

Populations often encounter changed environments that remove selection for the maintenance of particular phenotypic traits. The resulting genetic decay of those traits under relaxed selection reduces an organism's fitness in its prior environment. However, whether and how such decay alters the subsequent evolvability of a population upon restoration of selection for a previously diminished trait is not well...

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Identifiers

PMID: 31644535
DOI: 10.1371/journal.pbio.3000397
PMCID: PMC6827916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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