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Article

Antibiotic tolerance facilitates the evolution of resistance.

Science (New York, N.Y.) - 24 Feb 2017

Levin-Reisman Irit, Ronin Irine, Gefen Orit, Braniss Ilan, Shoresh Noam, Balaban Nathalie Q

Abstract excerpt

Controlled experimental evolution during antibiotic treatment can help to explain the processes leading to antibiotic resistance in bacteria. Recently, intermittent antibiotic exposures have been shown to lead rapidly to the evolution of tolerance-that is, the ability to survive under treatment without developing resistance. However, whether tolerance delays or promotes the eventual emergence of resistance is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28183996
DOI: 10.1126/science.aaj2191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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