Article

High-Throughput Evolution Unravels Landscapes of High-Level Antibiotic Resistance Induced by Low-Level Antibiotic Exposure

2023-12-01

Abstract excerpt

Potential pathogens consistently exposed to low-level environmental antibiotics could derive high-level clinically relevant resistance detrimental to the human health. However, the underlying evolutionary landscapes remain poorly understood. We conducted a high-throughput experimental evolution study by exposing an environmentally isolated pathogenic Escherichia coli strain to 96 typical antibiotics at 10 μg l −...

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Literature Corpus work: 4a456ac1-5ab0-5a50-8b7a-75e5122534d7
DOI: 10.1101/2023.11.30.569484

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