Back to search

Article

Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex

2023-06-02

Abstract excerpt

<h4>SUMMARY</h4> The prefrontal cortex (PFC) is critical for myriad high-cognitive functions and is associated with several neuropsychiatric disorders. Here, using Patch-seq and single-nucleus multiomic analyses, we identified genes and regulatory networks governing the maturation of distinct neuronal populations in the PFC of rhesus macaque. We discovered that specific electrophysiological properties exhibited d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a09116df-19cd-5742-8bf0-77789a071d55
DOI
10.1101/2023.06.02.543460
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortexDOI 10.1101/2023.06.02.543460
Select a neighboring publication to make it the new centre.