Article

Comparative molecular landscapes of immature neurons in the mammalian dentate gyrus across species reveal special features in humans

2025-02-17

Abstract excerpt

Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis contribute to plasticity, learning and memory, but their evolutionary changes across species and specialized features in humans remain poorly understood. Here we performed machine learning-augmented analysis of published single-cell RNA-sequencing datasets and identified macaque imGCs with transcriptome-wide immature neuronal charac...

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Literature Corpus work: e7036271-b0a2-534e-af50-ba1cc6d2b4fa
DOI: 10.1101/2025.02.16.638557

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