Article

Characterization of Electrophysiological and Transcriptomic Alterations in Patient-Derived Neurons from CHAMP1 Syndrome

2026-06-24

Abstract excerpt

<h4>ABSTRACT</h4> Mutations in chromosome alignment maintaining phosphoprotein 1 (CHAMP1) have been linked to neurodevelopmental disorders characterized by intellectual disability, developmental delay, and autism spectrum disorder. However, the cellular and electrophysiological mechanisms by which CHAMP1 mutations disrupt human neuronal development remain poorly understood. In the present study, we used patient-d...

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Literature Corpus work: d840ad86-7cda-52b7-a229-96aba03694de
DOI: 10.64898/2026.06.19.733368

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