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Article

scFv-Fcs as a Radiotheranostic Platform for Targeting TRA-1-60 in Pancreatic Cancers

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose:</bold> TRA-1-60 (TRA) is an established cancer stemness marker implicated in tumor initiation, therapeutic resistance, and disease relapse. It is minimally expressed in normal differentiated tissues, making it an appealing biomarker for immunopositron emission tomography (immunoPET) imaging and radiopharmaceutical therapy (RPT). Full-length monoclonal antibodies (mAbs)...

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Literature Corpus work
a02f4aef-3c63-528b-bd42-88e8f4a6be12
DOI
10.21203/rs.3.rs-10592835/v1
Open publication

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