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Article

Theranostic Radiopharmaceuticals Targeting Cancer-Associated Fibroblasts.

Current radiopharmaceuticals - 1 Jan 2021

Zhuravlev Fedor

Abstract excerpt

The tumor microenvironment is a dynamic ecosystem where malignant cells interact with the stromal cells sustaining and promoting tumor growth and metastasis. Cancer-associated fibroblasts (CAFs) are the major component of tumor stroma. CAFs control key tumorigenic activities by participating in immune evasion and suppression, extracellular matrix remodeling, neo-angiogenesis, and drug resistance. Therefore,...

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Identifiers

PMID: 33357190
DOI: 10.2174/1874471013666201224114148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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