Article

scFv-Fcs as a Radiotheranostic Platform for Targeting TRA-1-60 in Pancreatic Cancers

2026-08-27

Abstract excerpt

<title>Abstract</title> <p> Purpose TRA-1-60 (TRA) is an established cancer stemness marker implicated in tumor initiation, therapeutic resistance, and disease relapse. It is minimally expressed in normal differentiated tissues, making it an appealing biomarker for immunopositron emission tomography (immunoPET) imaging and radiopharmaceutical therapy (RPT). Full-length monoclonal antibodies (mAbs) often exhibit...

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Literature Corpus work: 80d3e05d-e7f2-54f5-921a-1391f68aaa70
DOI: 10.21203/rs.3.rs-10808760/v1

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