Article
Imaging Early-Stage Metastases Using an 18F-Labeled VEGFR-1-Specific Single Chain VEGF Mutant.
Molecular imaging and biology - 1 Jun 2021
Mason Christian A, Carter Lukas M, Mandleywala Komal, de Souza Franca Paula Demetrio, Meyer Jan-Philip, Mamun Tanjeena, Backer Joseph M, Backer Marina V, Reiner Thomas, Lewis Jason S
Abstract excerpt
PURPOSE: Metastatic breast cancer is the second leading cause of cancer-related death in women. The 5-year survival rate for metastatic breast cancer has remained near 26.9 % for over a decade. The recruitment of hematopoietic stem cells with high expression of the vascular endothelial growth factor receptor 1 (VEGFR-1) has been implicated in early stages of metastasis formation. We propose the use of an...
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