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Targeting the TRA-1-60 Glycoepitope Enables Selective ImmunoPET Imaging of Ovarian Cancer

2026-08-13

Abstract excerpt

Targeted radiopharmaceutical development for ovarian cancer (OC) has been limited by the lack of molecular targets that combine broad tumor expression with minimal normal-tissue distribution. TRA-1-60 (TRA) is a cancer-associated glycoepitope carried by podocalyxin. Here, we evaluated TRA as a target for OC and developed a TRA-directed immunoPET imaging platform. Immunohistochemical analysis demonstrated significa...

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Literature Corpus work
d5c4a353-bd36-5a8d-8b8c-69303f75f6b4
DOI
10.64898/2026.08.12.744522
Open publication

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