Article

A 68Ga–BCMA Ectodomain Tracer Enables PET/MR Longitudinal Tracking of Clinical-Grade BCMA/CD19 CAR T Cells

2026-05-15

Abstract excerpt

<title>Abstract</title> <p> CAR T cell therapies targeting CD19 and B cell maturation antigen (BCMA) induce profound responses in B cell malignancies, yet relapse highlight the need for non-invasive, quantitative tools to track cell kinetics. Here we develop an engineering-free, antigen-based PET/MR strategy to track tandem scFv BCMA/CD19 CAR-T product using a <sup>68</sup> Ga-labelled minimal BCMA ectodomain...

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Literature Corpus work: 3ff6cdb2-9144-5a01-b423-0b954246ee7a
DOI: 10.21203/rs.3.rs-9063774/v1

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