Article

Exploiting flow cytometry for the unbiased quantification of protein inclusions in <i>Caenorhabditis elegans</i>

2021-08-31

Abstract excerpt

The aggregation of proteins into inclusions or plaques is a prominent hallmark of a diverse range of pathologies including neurodegenerative diseases. The quantification of such inclusions in Caenorhabditis elegans models of aggregation is usually achieved by fluorescence microscopy or other techniques involving biochemical fractionation of worm lysates. Here, we describe a simple and rapid flow cytometry-based a...

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Literature Corpus work: a00f6eb0-9b04-52ff-88c0-9743ee6337a1
DOI: 10.1101/2021.08.29.458141

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