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Hound: A novel tool for automated mapping of genotype to phenotype in bacterial genomes assembled de novo

2023-09-16

Abstract excerpt

Increasing evidence suggests that microbial species have a strong within species genetic heterogeneity. This can be problematic for the analysis of prokaryote genomes, which commonly relies on a reference genome to guide the assembly process. Any difference between reference and sample genomes can introduce errors in the detection of small insertions, deletions, structural variations and even point mutations. This...

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Literature Corpus work
9fb5ef87-ea98-5f95-b07c-d06bf44798cf
DOI
10.1101/2023.09.15.557405
Open publication

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Hound: A novel tool for automated mapping of genotype to phenotype in bacterial genomes assembled de novoDOI 10.1101/2023.09.15.557405
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