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Article

Hound: a novel tool for automated mapping of genotype to phenotype in bacterial genomes assembled de novo.

Briefings in bioinformatics - 22 Jan 2024

Reding Carlos, Satapoomin Naphat, Avison Matthew B

Abstract excerpt

Increasing evidence suggests that microbial species have a strong within species genetic heterogeneity. This can be problematic for the analysis of prokaryote genomes, which commonly relies on a reference genome to guide the assembly process. Differences between reference and sample genomes will therefore introduce errors in final assembly, jeopardizing the detection from structural variations to point...

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PMID: 38385882
DOI: 10.1093/bib/bbae057
PMCID: PMC10883467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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